VOLUME 135 / 2018 : Preface vii // Chapter 1 Pathophysiology of Pyoderma Gangrenosum 1 - Nit in Tiwari, Tassici C. Koslopoulos, MD. am! Alex G. Ortega-Loayza, MD // Chapter 2 Oral Anticoagulants: Old and New Therapy 13 - Giuseppe Dattilo. Gabriella Falanga. Matteo Casale, Myriam D’Angelo, Salvina Quattrocchi. Annalisa Tamari. Michele Scorano, Egidio Imbalzano and Paolo Busacca // Chapter 3 Acute Gastroenteritis of Viral Etiology 71 - Vanda Bostik. Radek Šleha. Miloslav Salavec and Pavel Bostik // Chapter 4 One Step Beyond Towards Identifying “Aging Phenotypes” by Quantifying ?-Cell Receptor Excision Circles (TREC) 85 - Pierre Olivier Lang // Chapter 5 Therapeutic Efficacy of the Caspofungin for Candida and Aspergillus Species and Resistance Mechanisms 99 - Ana Maria R. de Carvalho Parahym, Carolina M. da Silva. Reginaldo G. Lima-Neto. Danielle P. C. Macčdo. Pedro José Rolim Neto and Rejane P. Neves // Chapter 6 Implication of V51y5T Cells in Operational Tolerance after Human Liver Transplantation 113 - Takaaki Koshiba. YingLi, Xiangdong Zhao. Hidenori Ohe, Hanna Nafady-Hego and G. Alex Bishop // Chapter 7 Clinical Utility of Caspofungin in Ocular Fungal Infections 129 - Chin Fen Neoh, Mark Danieli, Elsie Chan, Pei Fang Neoh, and David CM Kong // Index 159