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0 (hodnocen0 x )

EB

EB

ONLINE

Cham : Springer : Humana Press, 2017

1 online zdroj

ISBN 978-3-319-46038-3 (e-kniha)

ISBN 978-3-319-46036-9 (print)

Contemporary Endocrinology

Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT and PET/CT and PET/MR. Discussing of radionuclide imaging covers the tumors mentioned above, as well as pulmonary and thymic neuroendocrine tumors and medullary thyroid carcinoma. A presentation of radionuclide therapies follows, including 131I-MIBG therapy, somatostatin receptor-based therapy, and alpha radionuclide therapy, as well as the role of nanoparticles. Comprehensive and up-to-date, Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors will assist and guide physicians who encounter patients with these conditions, either from a diagnostic or therapeutic standpoint, and particularly emphasizes the current and emerging medical devices and imaging and therapeutic options..

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Classification of neuroendocrine tumors -- Molecular genetics of Pheochromocytoma and paraganglioma -- Molecular Genetics of MEN1-related Neuroendocrine Tumors -- Molecular genetics of MEN2-related neuroendocrine tumors -- Molecular genetics of Neuroblastoma -- Molecular Genetics of Gastroenteropancreatic Neuroendocrine Tumors -- Current and future radiopharmaceuticals in neuroendocrine tumors imaging -- SPECT/CT, PET/CT and PET/MR: Principles -- Internal dosimetry: Principles and Applications to NET -- Principles and Application of Molecular Imaging for Personalised Medicine and Guiding Interventions in Neuroendocrine Tumors -- Tumor metabolism and metabolomics of pheochromocytomas and paragangliomas -- Radionuclide imaging of pheochromocytoma and paraganglioma in the era of multi-omics -- Radionuclide imaging of Head and neck PGLs -- Radionuclide imaging of Chromaffin cell tumors -- Radionuclide imaging of Gastrointestinal neuroendocrine tumors -- Radionuclide imaging of Pancreatic neuroendocrine tumors -- Radionuclide imaging of Pulmonary, thymic neuroendocrine tumors and other neuroendocrine tumors -- Radionuclide imaging of Medullary thyroid carcinoma -- 131I-MIBG therapy for pheochromocytoma/paraganglioma and neuroblastoma -- Somatostatin receptors-based radionuclide therapy -- Alpha radionuclide therapy: Principles and Applications to NET -- Nanoparticles for Radionuclide Imaging and Therapy: Principles.